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In endometriosis, there is a risk of female infertility of up to 30% to 50%.〔(Endometriosis: Does It Cause Infertility? ), from American Society for Reproductive Medicine. Revised 2012〕 ==Mechanism== The mechanisms by which endometriosis may cause infertility is not clearly understood, particularly when the extent of endometriosis is low. Still possible mechanisms include: *Anatomical distortions and adhesions (the fibrous bands that form between tissues and organs following recovery from an injury) *The release of factors from endometriotic cysts which are detrimental to gametes or embryos. An endometriotic cyst contains free iron, reactive oxygen species, proteolytic enzymes and inflammatory molecules.〔 Follicular density in tissue surrounding the endometriotic cyst has been consistently shown to be significantly lower than in healthy ovaries, and to a degree that does not appear to be caused merely by the stretching of surrounding tissues owing to the presence of a cyst. The other way around, endometriosis may more likely develop in women who fail to conceive for other reasons and thus be a secondary phenomenon. For this reason it is preferable to speak of "endometriosis-associated infertility" rather than any definite "infertility caused by endometriosis" by the same reason that association does not imply causation. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Endometriosis and infertility」の詳細全文を読む スポンサード リンク
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